Visio 2010 was one of the first versions to offer a native 64-bit installer, designed to handle larger, more complex diagrams by utilizing more system memory.
Since there is no official standalone portable version, you can achieve similar "on-the-go" results through these supported methods: Visio 2010 Viewer : If you only need to view or print diagrams without installing the full software, use the Visio 2010 Viewer
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